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May 23, 2010

Health Tip: When Diaper Rash Needs a Doctor

Filed under: Health Tip — admin @ 7:59 am

Diaper rash is usually managed and treated at home without a doctor’s supervision. There are cases, however, when it’s best to call a pediatrician.

The American Academy of Family Physicians offers these warning signs that diaper rash should be evaluated by a doctor:
The rash breaks out when the baby is 6 weeks or younger.
The rash has small ulcers or pimples.
The rash is accompanied by fever, nodules or large bumps.
The infant doesn’t look well or has lost weight.
The rash spreads beyond the diaper area, including to the scalp, face or arms.
The rash doesn’t improve with treatment after a week.

May 22, 2010

Health Tip: Warning Signs of Carbon Monoxide Poisoning

Filed under: Health Tip — admin @ 7:59 am

Carbon monoxide is a colorless, odorless toxic gas. It’s released by the burning of any fuel, and exposure can lead to hospitalization or even death.

The U.S. Centers for Disease Control and Prevention offers this list of common symptoms of carbon monoxide poisoning:
Vomiting or feeling nauseous.
Feeling dizzy.
Having chest pains.
Having a headache.

While none of these symptoms should be ignored, warning signs of more severe carbon monoxide poisoning include confusion, agitation or unconsciousness. They require immediate medical attention.

April 29, 2010

Ambidextrous Children at Higher Risk for Learning Problems

Filed under: General — admin @ 1:16 am

Ambidextrous children are more likely to have attention-deficit/hyperactivity disorder (ADHD), problems with language and schoolwork, and other mental health issues than right-handed children, new research suggests.

Children are considered ambidextrous if neither hand is dominant, where they switch between using the right and left hands for activities such as eating or writing, or they use their right hand for certain activities and the left for others.

In the study, researchers analyzed data on nearly 8,000 children born in 1985-1986 who participated in the Northern Finland Birth Cohort. Language difficulties, scholastic performance and mental health issues were assessed between ages 7 and 8 and again at age 16 through reports of symptoms from teachers, parents and the children themselves.

At age 8, children who were “mixed-handed” were twice as likely as right-handed children to have difficulties with schoolwork or language, such as with reading or their ability speak as well as their peers.

At age 16, mixed-handed children were twice as likely to have problems with language at school and scores on assessment tests indicating they likely had ADHD. Symptoms of ADHD include excessive fidgeting, inability to focus on a task or concentrate, impulsivity and poor school performance.

Mixed-hand children were also more likely to have signs of psychiatric disturbances, the researchers found.

The study authors noted that mixed-handedness could be useful in diagnosing children with ADHD and other mental health issues.

“Mixed-handedness together with the presence of behavioral problems can be a red flag,” said study author Alina Rodriguez, of the department of psychology at Uppsala University in Sweden. “However, mixed-handedness alone does not necessarily imply that the child has problems. Mixed-handedness is one of a host of other known risk factors.”

The study is published in the Jan. 25 online issue of Pediatrics.

About 1 percent of children in the study were identified by their parents as being mixed-handed, while about 8 percent of kids were left-handed. The researchers found no association with being left-handed and any of the scholastic or mental health impairments.

One explanation for why mixed-handed children may be more prone to language difficulties and ADHD is because being ambidextrous is a proxy for atypical cerebral lateralization, or differences in the structure and function of the brain.

The brain is normally specialized, Rodriguez explained, with the left hemisphere of the brain dominant in right-handed people. Mixed-handed people, however, have differences in the typical dominance pattern of the brain.

Prior research has suggested that children with dyslexia and with ADHD have disturbances in the right hemisphere.

Though the study is interesting, it’s probably of limited use as a diagnostic tool, said Dr. Andrew Adesman, chief of developmental and behavioral pediatrics at Schneider Children’s Hospital in New Hyde Park, N.Y.

Most of the mixed-handed children in the study did not have ADHD, scholastic difficulties or any other mental health issues, he noted. And the majority of children who had ADHD or problems at school were not mixed-handed.

Still, it’s an area that merits further research, Adesman said.

“Handedness has a relationship to brain development, and brain development has a relationship to ADHD and dyslexia,” Adesman said. “The data support the idea that there seems to be an increased association between mixed-handedness and learning-attentional problems.”

SOURCES: Andrew Adesman, M.D., chief, developmental and behavioral pediatrics, Schneider Children’s Hospital, New Hyde Park, N.Y.; Alina Rodriguez, Ph.D., department of psychology, Uppsala University, Uppsala, Sweden;

April 24, 2010

U.S. Bans Texting by Truck and Bus Drivers

Filed under: Uncategorized — admin @ 5:16 pm

Truck and bus drivers who travel interstate roadways are now banned from using a handheld device to send text messages, U.S. officials said Tuesday.

The ban, which is supported by the trucking and bus industry, goes into effect immediately, with violators subject to up to $2,750 fines, U.S. Transportation Secretary Ray LaHood said during a morning press conference.

“We said the federal government would do everything in its power to send a clear message that texting, talking and driving are potentially lethal activities with very serious consequences,” LaHood said. “Today we are sending a strong message. We don’t merely expect you to share the road responsibly with other travelers — we will require you to do so.”

More than 500,000 people were injured and nearly 6,000 people were killed last year in motor-vehicle accidents involving a driver who was distracted while using a cell phone or texting device, according to the U.S. Department of Transportation.

The hardest part of banning texting and talking on cell phones is enforcement, LaHood admitted. However, he noted that laws requiring seat belts and the laws against drunken driving were also hard to enforce at the start, but raising awareness has helped to get more people to use seat belts and not drive drunk.

LaHood hinted that the cell phone industry might find ways that would alert police that a driver was texting or talking on a cell phone.

Research from the Federal Motor Carrier Safety Administration found that drivers sending and receiving text messages take their eyes off the road for about 4.6 seconds out of every 6 seconds while texting, Anne Ferro, the agency’s administrator, said during the press conference.

At that rate, a driver going 55 miles an hour would travel the length of a football field, including the end zones, without looking at the road, she said.

People who text while driving are 23 times more likely to get in an accident than non-distracted drivers, LaHood said. The agency is working on more regulation to reduce the use of cell phones and other electronic devices among interstate truck and bus drivers, Ferro added.

William P. Graves, president of the American Trucking Association (ATA), said during the press conference: “We realize that texting on a handheld phone or wireless device while driving substantially elevates the risk of being involved in an accident. ATA does support DOT’s action to ban the use of handheld wireless devices by commercial drivers while driving to send or receive text messages.”

In September, President Barack Obama signed an executive order prohibiting federal employees from using cell phones or sending text messages while driving government-owned vehicles or with government-owned equipment. The ban took effect Dec. 30, LaHood said.

April 20, 2010

Treadmill helps Parkinson’s patients walk better

Filed under: General — admin @ 5:04 pm

Treadmill training can help Parkinson’s patients to walk more normally, according to a new review of the medical literature.

However, it’s unclear how long the benefits of treadmill training will last, or the best way to deliver this type of training to patients with the movement disorder, Dr. Jan Mehrholz of the Wissenschaftliches Institut in Kreischa, Germany and colleagues note.

In Parkinson’s disease, neurons producing dopamine, an important chemical messenger in the brain, die off, leading to movement problems, tremor and rigidity. Many Parkinson’s patients have a characteristic shuffling gait, which can boost their risk of falls and fractures.

Treadmill training has been used to help improve gait in Parkinson’s patients, but more information is needed on its effectiveness and safety, Mehrholz and colleagues say. To investigate, they identified eight studies that compared treadmill training to no treadmill training in a total of 203 Parkinson’s patients.

Their analysis found that training significantly improved walking speed, stride length and walking distance. However, it did not improve the “cadence,” or rhythm, of a patient’s gait.

The evidence should be interpreted with caution, Mehrholz and colleagues say, because it’s based on only eight small studies.

“There is still a need for larger trials to establish if treadmill training can be safely used as a routine therapy for Parkinson’s patients,” Mehrholz said in a statement accompanying the study published in The Cochrane Library, a publication of the Cochrane Collaboration, an international non-profit that evaluates medical research.

“We also need to answer basic questions,” Mehrholz said, “about how long the benefits last and what a good training program should consist of. For instance, how often and how long should patients train for?”

SOURCE: The Cochrane Library 2010.

March 27, 2010

Health Tip: These Symptoms May Indicate Uterine Fibroids

Filed under: Uncategorized — admin @ 9:18 pm

Uterine fibroids are growths that form inside a woman’s uterus. Though they’re not cancerous, they can cause pain and other symptoms.

The American Congress of Obstetricians and Gynecologists says the following warning signs may indicate uterine fibroids:
Menstrual bleeding that is heavier, occurs more often or lasts longer than normal.
Menstrual cramps.
Spotting or bleeding between periods.
Anemia.
Painful intercourse.
Pain in the abdomen or lower back.
Difficult or frequent urination.
Constipation, or pain during bowel movements.
Infertility or miscarriage.
Enlargement of the uterus and abdomen.

March 20, 2010

FDA Approves Generic Aricept to Treat Dementia Related to Alzheimer’s Disease

Filed under: Uncategorized — admin @ 9:17 pm

Please note this is a corrected version of a press release that was posted to FDA’s website today. The corrections include a modified headline and a revised second paragraph.

The U.S. Food and Drug Administration approved the first generic versions of Aricept (donepezil hydrochloride) orally disintegrating tablet s on Dec. 11. Donepezil hydrochloride is indicated for the treatment of dementia related to Alzheimer’s disease.

Orally disintegrating tablets dissolve on the tongue, without having to be swallowed whole. This may make it easier to take the medication for older or disabled patients who have difficulty swallowing.

“Generics offer greater access to health care for all Americans,” said Gary Buehler, director of the FDA’s Office of Generic Drugs. “Health care professionals and consumers can be assured that FDA-approved generic drugs have met the same rigorous standards as the brand-name drug and are the same as the branded in dosage form, safety, strength, route of administration, quality, performance characteristics and intended use.”

Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with Alzheimer’s disease, symptoms first appear after age 60. Alzheimer’s disease is the most common cause of dementia among older people, but it is not a normal part of aging.

Dementia refers to a decline in cognitive function that interferes with daily life and activities. Alzheimer’s disease starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain.

The generic donepezil hydrochloride orally disintegrating tablets, manufactured by Mutual Pharmaceutical of Philadelphia, have been approved in 5 milligram and 10 mg strengths.

March 13, 2010

Gene Variant Seems to Guard Against Asthma, COPD

Filed under: Uncategorized — admin @ 9:17 pm

A gene variant that plays a role in inflammation seems to protect the lungs of children with asthma as well as adults who smoke.

Researchers also found that adult smokers with this variant of the MMP12 gene had a lower risk of developing chronic obstructive pulmonary disease (COPD), a progressive condition often brought on by smoking.

“The gene seems to be protective of the lungs in both asthma and COPD,” said Dr. Norman Edelman, chief medical officer of the American Lung Association.

Any new gene identified raises the hope that it will provide ways to prevent or treat the disease to which it is allied and this is no exception.

“Levels of the MMP12 gene may impact the quality of life for those individuals with asthma and COPD, and may allow us to come up with potential therapeutic approaches,” added Jeffrey Cirillo, professor of microbial and molecular pathogenesis at Texas A&M Health Science Center College of Medicine in College Station. “By understanding more about this specific gene we can find ways to induce or oppress that protein expression in the lungs.”

“The real question is not why people who smoke get COPD. We kind of know the answer to that. The question is why do people who don’t smoke get COPD,” added Edelman. “If we understood that, we could find ways to reverse it and protect people.”

The MMP12 gene has been implicated in the development of emphysema in mice that are exposed to smoke, suggesting that the gene may also be important in the onset of emphysema in humans. The gene is also linked with other genes involved in asthma.

This information, combined with the fact that factors that can cause the onset of asthma in children are also involved with how well your lungs function in adulthood spurred investigators to undertake this study.

Dr. Juan C. Celedon, an associate professor of medicine at Brigham and Women’s Hospital and Harvard Medical School in Boston and his colleagues looked at seven different groups of people, in all comprising 8,300 children and adults.

A variant of MMP12 was associated with better lung function in children with asthma.

In adults, the variant led to better lung function in adult smokers and reduced the risk of COPD in former or current smokers.

The findings, published online Dec. 16 in the New England Journal of Medicine, also shed new light on the connections between asthma and COPD.

“This suggests that there are some genes that may influence both asthma and COPD, so that for a subgroup of people there may be common determinants,” said study senior author Celedon.

“There is certainly overlapping in that how you get asthma and how you get COPD is related and probably very closely related,” Cirillo said. “That’s exciting because it suggests that if we can decrease or increase expression of genes that are common to both, we could potentially affect both. It’s nice to have one treatment.”

All of which makes sense, Edelman said. “This gene is involved in the inflammatory process, and asthma is a disease of inflammation and COPD is a disease of inflammation,” he noted. “The results are different and the pathways are different but you’re still talking about inflammation of the lung. It’s not terribly surprising that it appears to be protective in both circumstances.”

February 28, 2010

Swine Flu May Hit Kids With Asthma Harder

Filed under: Uncategorized — admin @ 7:09 pm

Canadian researchers are reporting that children with asthma are more likely to develop severe cases of H1N1 flu than seasonal flu.

“Asthma has been identified as a significant risk factor for admission with pandemic H1N1 influenza, present in 21 percent to 30 percent in the larger samples,” wrote Dr. Upton Allen and fellow researchers from the Hospital for Sick Children in Toronto.

Their study was published online Nov. 19 in the Canadian Medical Association Journal.

The finding stemmed from a comparison of medical data on 58 children admitted to the Toronto hospital with H1N1 flu, sometimes called swine flu, from May 8 to July 22 this year and data on 200 children who were admitted for seasonal flu from 2004 to 2009.

Of the children treated for H1N1 flu, 22 percent had asthma, but just 6 percent of those treated for seasonal flu had asthma, the study found. Also, almost half of the children admitted to the intensive care unit to be treated for H1N1 flu had asthma.

The researchers described the prevalence of asthma as “the most striking difference” between the two groups of children, but they found other differences as well. Children with H1N1 flu were older. But children with both kinds of flu spent about the same amount of time in the hospital: four days.

None of the children with H1N1 flu died; one child with seasonal flu died, the study reported.

February 22, 2010

For Kids With Down Syndrome, a ‘Ray of Hope’

Filed under: Uncategorized — admin @ 7:09 pm

New research may provide the foundation for future medical treatment of memory deficits associated with Down syndrome.

The research was conducted in mice that were genetically engineered to have a condition similar to Down syndrome, a genetic disorder. It is still not clear if humans would benefit from the findings.

Still, the researchers found that mice with the syndrome-like condition could use their brains more effectively when the signaling of norepinephrine, a neurotransmitter that helps nerve cells communicate, was boosted.

“If you intervene early enough, you will be able to help kids with Down syndrome to collect and modulate information,” Dr. Ahmad Salehi, the study’s primary author, said in a news release from Stanford University Medical Center. “Theoretically, that could lead to an improvement in cognitive functions in these kids.” Salehi, a research health science specialist at the Veterans Affairs Palo Alto Health Care System, in California, was a senior scientist at Stanford when the study was conducted.

The study found that the mice did better on cognitive tests such as nest-building — in fact, as well as normal mice — after getting drugs that boosted norepinephrine levels.

“We were very surprised to see that, wow, it worked so fast,” Salehi said. The results were published in Science Translational Medicine.

The study results give “a ray of hope and optimism for the Down syndrome community for the future,” Dr. Melanie Manning, director of the Center for Down Syndrome at Lucile Packard Children’s Hospital, said in the news release.

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